Recombinant Human ENA-78 (CXCL5) (8-78 a.a.) 0 리뷰Submit a Review 제품 상세 카다로그 번호 300-22B 제품 설명 ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The three naturally occuring variants of human ENA-78; ENA 5-78, ENA 8-78, ENA 9-78, contain 74, 71, and 70 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokines that bind to the CXCR1 and CXCR2 receptors. Recombinant Human ENA-78 is a 7.8 kDa protein consisting of 71 amino acid residues. Source: E.coli Synonyms: Epithelial Neutrophil Activating Peptide-78, CXCL5 AA Sequence: LRELRCVCLQ TTQGVHPKMI SNLQVFAIGP QCSKVEVVAS LKNGKEICLD PEAPFLKKVI QKILDGGNKE N Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P42830 Gene ID: 6374 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human References PubMed SDS CoA 검색 Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Wound Healing product.subtitle.recentcitations 제 1 저자 Lee, A W 주제 A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. 인용 The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed ID 31167786 제 1 저자 Alenazi, Y 주제 Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. 인용 Scientific Reports; 8(1) pg6333 PubMed ID 29679010
