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  4. Recombinant Human FGF-basic (154 a.a.)

Recombinant Human FGF-basic (154 a.a.)

제품 상세

카다로그 번호 100-18B
제품 설명
Recombinant Human FGF-basic (154 a.a.)

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.
Qualified for stem cell use.

Source: E.coli

Synonyms: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin

AA Sequence: AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

This product has been tested against the WHO standard. International Unit information can be found here.

Recombinant Human FGF-basic (154 a.a.) Biological Activity Graph

Calculated Molecular Weight: 17.2 kDa

Accession Number: P09038

Gene ID: 2247

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Alpaca, Bacteria, Chicken, Cow, Dog, Frog, Guinea Pig, Hamster, Horse, Human, Human + Hamster, Human + Mouse, Human + Rat, Human + Virus, Monkey, Mouse, Mouse + Chicken, Mouse + Pig, Mouse + Rat, Pig, Rabbit, Rat, Rat + Chicken, Sheep
Country Of Origin: USA

Not for human use.

Research Interest
Organoids Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer Cell Culture FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Diabetes/Weight Regulation

product.subtitle.recentcitations

제 1 저자
Fu, H
주제
Thrombospondin 1 missense alleles induce extracellular matrix protein aggregation and TM dysfunction in congenital glaucoma.
인용
The Journal of Clinical Investigation; 132(23)
PubMed ID
36453543
제 1 저자
Niu, Y
주제
Multiparametric and accurate functional analysis of genetic sequence variants using CRISPR-Select.
인용
Nature Genetics; 54(12) pg1983-1993
PubMed ID
36471068
제 1 저자
Zhang, Z
주제
Ti3 C2 Tx MXene Composite 3D Hydrogel Potentiates mTOR Signaling to Promote the Generation of Functional Hair Cells in Cochlea Organoids.
인용
Advanced science (Weinheim, Baden-Wurttemberg, Germany); 9(32) pge2203557
PubMed ID
36117048

product.subtitle.productreviews

기존 리뷰
Excellent for iPS endothelial differentiation
Yet another excellent product by PeproTech! This recombinant human FGF is used at 20ng/mL with VEGF for iPS endothelial (EC) differentiation to generate high quality ECs.
에서:  DIlip | 날짜:  2020-07-13
Very good for stem cell maintenance
Very good product for human stem cell and cancer stem cell maintenance and proliferation, of higher quality than similar product of competitors!
에서:  stefania | 날짜:  2020-08-05
Another great iPSC differentiation growth factor!
I have found this product to remain exceptionally stable in media and give good, reproducible results when I am differentiating human iPSCs. Plus, the product ships quickly (which is important when I realize I am running low on growth factors). Thank you Peprotech for quality products and fast service!
에서:  Kendall | 날짜:  2020-08-26
review for bFGF
We have been purchasing bFGF from Peprotech for the past 5 years and the product is very reliable. We've never had a problem. The tech support has been very helpful.
Thank you,
에서:  Yingzi | 날짜:  2021-08-03
Great for organoids!
High quality product for patient tumor organoids.
에서:  Julie-Ann | 날짜:  2021-08-03
Excellent product. We use it standardly for our primary cell cultures
Easy to use. We have used it in our standard TC medium for our primary cells for years.
에서:  Helen | 날짜:  2021-08-09
Stem Cell Culture
Very consistent for culturing
에서:  Danielle | 날짜:  2021-08-24
Constant quality for in vitro culture
Using in in vitro culture. Constant quality. Also swift delivery.
에서:  KOHSUKE | 날짜:  2021-08-24
FGF, human basic recombinant, E. coli
Using the FGF in culture medium now for 6 years and very satisfied. Good quality and good customer support from Peprotech. Keep up the good work !
에서:  Arjan | 날짜:  2021-08-27
Great recombinant protein
Works very nicely in combination with EGF to keep mouse ESC-derived NPCs alive and proliferating in culture (at 10 ng/ml concentration). Highly recommend.
에서:  Epp | 날짜:  2021-08-31