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Chemokines

Recombinant Human GRO-γ (CXCL3)

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제품 상세

카다로그 번호 300-40
제품 설명
Recombinant Human GRO-γ (CXCL3)

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Human GRO-γ is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Source: E.coli

Synonyms: Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSA γ), CXCL3, MIP-2β, GRO3

AA Sequence: ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract 293 transfected CXCR2 cells using a concentration range of 10-100 ng/ml.

Recombinant Human GRO-γ (CXCL3) Biological Activity Graph

Calculated Molecular Weight: 7.9 kDa

Accession Number: P19876

Gene ID: 2921

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Lee, A W
주제
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
인용
The Journal of Biological Chemistry; 294(29) pg11199-11212
PubMed ID
제 1 저자
Alenazi, Y
주제
Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.
인용
Scientific Reports; 8(1) pg6333
PubMed ID
제 1 저자
Singh, K
주제
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
인용
Scientific Reports; 7(1) pg4267
PubMed ID