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Animal-Free Cytokines

Animal-Free Recombinant Human PlGF-1

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제품 상세

카다로그 번호 AF-100-06
제품 설명
Animal-Free Recombinant Human PlGF-1

PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, the colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration. Recombinant Human PlGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 132 amino acid polypeptide chains.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Placenta Growth Factor-1, PlGF, PGF

AA Sequence (monomer): MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human monocytes of using a concentration range of 1.0-10.0 ng/ml.

Animal-Free Recombinant Human PlGF-1 Biological Activity Graph

Calculated Molecular Weight: 29.7 kDa

Accession Number: P49763

Gene ID: 5228

Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Ugarte-Berzal, E
주제
VEGF/VEGFR2 interaction down-regulates matrix metalloproteinase-9 via STAT1 activation and inhibits B chronic lymphocytic leukemia cell migration.
인용
Blood; 115(4) pg846-9
PubMed ID