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Animal-Free Cytokines

Animal-Free Recombinant Human RANTES (CCL5)

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제품 상세

카다로그 번호 AF-300-06
제품 설명
Animal-Free Recombinant Human RANTES (CCL5)

RANTES is a CC chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus
receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant Human RANTES is a 7.8 kDa protein containing 68 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Regulation upon Activation Normal T cell Express Sequence, CCL5, SIS-delta

AA Sequence: SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human blood monocytes using a concentration range of 1.0-10.0 ng/ml.

Calculated Molecular Weight: 7.8 kDa

Accession Number: P13501

Gene ID: 6352

Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Whittall, C
주제
A chemokine self-presentation mechanism involving formation of endothelial surface microstructures.
인용
Journal of immunology (Baltimore, Md. : 1950); 190(4) pg1725-36
PubMed ID
제 1 저자
Swaminathan, G
주제
A role for microRNA-155 modulation in the anti-HIV-1 effects of Toll-like receptor 3 stimulation in macrophages.
인용
PLoS Pathogens; 8(9) pge1002937
PubMed ID
제 1 저자
Yang, D
주제
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
인용
The Journal of Experimental Medicine; 209(1) pg157-71
PubMed ID