Recombinant Rat SDF-1α (CXCL12) 0 리뷰Submit a Review 제품 상세 카다로그 번호 400-32A 제품 설명 SDF-1α and β are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1α and β contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1α protein is the result of alternative splicing of the SDF-1 gene and contains 68 amino acid residues. Recombinant Rat SDF-1α is a 7.9 kDa protein containing 68 amino acid residues. Source: E.coli AA Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNK Synonyms: Stromal-Cell Derived Factor-1, CXCL12, PBSF Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50.0-100.0 ng/ml. Calculated Molecular Weight: 7.9 kDa Accession Number: Q9QZD1 Gene ID: 24772 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Human + Rat, Rat References PubMed SDS CoA 검색 Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Chemotaxis Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations 제 1 저자 Pouzol, L 주제 ACT-1004-1239, a first-in-class CXCR7 antagonist with both immunomodulatory and promyelinating effects for the treatment of inflammatory demyelinating diseases. 인용 FASEB journal : official publication of the Federation of American Societies for Experimental Biology; 35(3) pge21431 PubMed ID 33595155 제 1 저자 Jayasuriya, C T 주제 Human Cartilage-Derived Progenitors Resist Terminal Differentiation and Require CXCR4 Activation to Successfully Bridge Meniscus Tissue Tears. 인용 Stem cells (Dayton, Ohio); 37(1) pg102-114 PubMed ID 30358021 제 1 저자 Renko, O 주제 SDF1 gradient associates with the distribution of c-Kit+ cardiac cells in the heart. 인용 Scientific Reports; 8(1) pg1160 PubMed ID 29348441
