Recombinant Human GDF-7 0 ReviewsSubmit a Review Product Details Catalog Number: 120-37 Description: GDF-7 belongs to the TGF-β superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissues. Recombinant Human GDF-7 is a 28.0 kDa disulfide-linked homodimer containing two 129 amino acid residues. Source: E.coli Synonyms: Growth/Differentiation Factor-7, BMP-12 AA Sequence (monomer): TALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. Calculated Molecular Weight: 28 kDa Accession Number: Q7Z4P5 Gene ID: 151449 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Bone, Skeletal, Cartilage Cell Culture Immune System Neurobiology TGF-β Superfamily Recent Citations First Author Armandari, I Title CREB signaling activity correlates with differentiation and survival in medulloblastoma Citation Scientific Reports; 11(1) pg16077 PubMed ID 34373489 First Author Boisvert, E M Title The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells. Citation Scientific Reports; 5 pg16821 PubMed ID 26581770
