Recombinant Human MCP-3 (CCL7) 0 ReviewsSubmit a Review Product Details Catalog Number: 300-17 Description: The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-3 is a 9.0 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. Source: E.coli Synonyms: Monocyte Chemotactic Protein-3, CCL7, MARC AA Sequence: QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 9 kDa Accession Number: P80098 Gene ID: 6354 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Bacteria, Hamster, Human, Human + Rat, Monkey, Mouse, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Cancer Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy Recent Citations First Author Darlot, B Title Engineered anti-inflammatory peptides inspired by mapping an evasin-chemokine interaction. Citation The Journal of Biological Chemistry; 295(32) pg10926-10939 PubMed ID 32471866 First Author Lee, A W Title A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. Citation The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed ID 31167786 First Author Alenazi, Y Title Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. Citation Scientific Reports; 8(1) pg6333 PubMed ID 29679010
