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Growth Factors & Cytokines

Recombinant Human Prolactin

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Product Details

Catalog Number: 100-07
Description:
Recombinant Human Prolactin

Prolactin is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, prolactin plays an immunoegulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant Human Prolactin is a 23.0 kDa globular protein containing 200 amino acid residues.

Source: E.coli

Synonyms: Mammotropin, Luterotropic hormone, Lutetropin

AA Sequence: MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYTHGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR SWNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQVHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HKIDNYLKLL KCRIIHNNNC

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.

Recombinant Human Prolactin Biological Activity Graph

Calculated Molecular Weight: 23 kDa

Accession Number: P01236

Gene ID: 5617

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Cross Reactivity Cited in References:
Country Of Origin: USA

Not for human use.

Research Interest

Recent Citations

First Author
Wang, Q
Title
UDP-glucose dehydrogenase expression is upregulated following EMT and differentially affects intracellular glycerophosphocholine and acetylaspartate levels in breast mesenchymal cell lines.
Citation
Molecular Oncology; 16(9) pg1816-1840
PubMed ID
First Author
Wang, Q
Title
Glutamine-Fructose-6-Phosphate Transaminase 2 (GFPT2) Is Upregulated in Breast Epithelial-Mesenchymal Transition and Responds to Oxidative Stress.
Citation
Molecular & cellular proteomics : MCP; 21(2) pg100185
PubMed ID
First Author
Shee, K
Title
Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer.
Citation
The Journal of Experimental Medicine; 215(3) pg895-910
PubMed ID