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Monoklonale Antikörper


Anti-Human CD184 (CXCR4) Purified (Clone#: 12G5)


Katalognummer: 16911-20
The 12G5 monoclonal antibody specifically bind to human CD184 (CXCR4), a seven-transmembrane G-protein-coupled receptor. It is widely expressed on endothelial cells, hematopietic cells, and also on naïve T cell subsets. CD184 is the receptor for SDF-1 and an alternative receptor for HIV-1. The 12G5 antibody is reported to inhibit SDF-1 induced chemotaxis and calcium influx and some CD4-dependent infections of HIV-1.

Source: Isotype: Mouse IgG2a, kappa; Clone#: 12G5


Product supplied by Biogems

crossreactivity: Research Interest

Country Of Origin: USA

Not for human use.