Animal-Free Recombinant Human IL-5 0 ReviewsSubmit a Review Product Details Catalogue Number: AF-200-05 Description: IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 are cross-species reactive. Recombinant Human IL-5 is a 26.5 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Interleukin-5, EDF, BCDFII, TRF AA Sequence (monomer): MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 0.15 ng/ml, corresponding to a specific activity of ≥ 6.6 x 106 units/mg. Calculated Molecular Weight: 26.5 kDa Accession Number: P05113 Gene ID: 3567 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Immune System Inflammation Stem Cells & Differentiation Wound Healing Allergy
