Murine IL-1β Pre-Coated ELISA Kit Product Details Catalogue Number: BGK10749 Description: IL-1β is a proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. The BioGems Murine IL-1β Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure Murine IL-1β with a 96-well strip plate that is pre-coated with rat monoclonal antibody specific for IL-1β. It contains E.coli-expressed recombinant Murine IL-1β. The detection antibody is a biotinylated goat polyclonal antibody specific for IL-1beta. The kit is analytically validated with ready to use reagents. Sandwich ELISA: Assay Type: Solid Phase Sandwich ELISA: 96-Well Strip Plate Sensitivity: <1 pg/ml Range: 12.5 pg/mL- 800 pg/mL Specificity: Natural and recombinant Murine IL-1ß Uniprot: P10749 Interference: No detectable cross-reactivity with other relevant proteins Note: Product supplied by Biogems Country Of Origin: USA Not for human use. CoA Search Product Line
