Small Molecules

Biogems

Rapamycin

Produktdetails

Katalognummer: 5318893
Beschreibung:

Rapamycin was first evaluated as an antifungal agent, but is now studied for its potent immunosuppressive and antiproliferative properties. It forms a complex with FKBP12 and directly binds to mTORC1, inhibiting the functions of the mTOR pathway. Rapamycin is reported to block protein synthesis, arrest cell cycle progression, and inhibit IL-2 signal transduction mechanisms.

Synonyms: Sirolimus, Rapamune, AY 22989

Application:

Formulation:
Crystalline solid
Chemical Name:
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)­9,10,12,13,14,21,22,23,24,25,26,27,32,33,34, 34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2­[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy­6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4] oxaazacyclohentriacontine­1,5,11,28,29 (4H,6H,31H)-pentone
Molecular Formula:

C51H79NO13

Molecular Weight:
914.2
CAS Number:
53123-88-9
Purity:
≥95%

Note:

Product supplied by Biogems

Research Interest

Country Of Origin: USA

Not for human use.