Wachstumsfaktoren & Zytokine

Recombinant Human FGF-16

Product Details

Catalogue Number: 100-29
Description:
Recombinant Human FGF-16

FGF-16 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system. Recombinant Human FGF-16 is a 23.6 kDa protein consisting of 206 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-16, FGFG

AA Sequence: AEVGGVFASL DWDLHGFSSS LGNVPLADSP GFLNERLGQI EGKLQRGSPT DFAHLKGILR RRQLYCRTGF HLEIFPNGTV HGTRHDHSRF GILEFISLAV GLISIRGVDS GLYLGMNERG ELYGSKKLTR ECVFREQFEE NWYNTYASTL YKHSDSERQY YVALNKDGSP REGYRTKRHQ KFTHFLPRPV DPSKLPSMSR DLFHYR

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 106 units/mg.

Calculated Molecular Weight: 23.6 kDa

Accession Number: O43320

Gene ID: 8823

Note:

250μg is the largest vial size for this product.
Larger sizes supplied as multiple 250μg vials.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Savchenko, E
Title
FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes.
Citation
Scientific Reports; 9(1) pg9610
PubMed Id
First Author
Westphal, S
Title
Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes.
Citation
Scientific Reports; 9(1) pg8470
PubMed Id
First Author
Duan, Y
Title
Fibroblast growth factor 16 stimulates proliferation but blocks differentiation of rat stem Leydig cells during regeneration.
Citation
Journal of Cellular and Molecular Medicine; 23(4) pg2632-2644
PubMed Id

product.subtitle.productreviews

Existing reviews
Recombinant human FGF-16 for primary rat cardiomyocyte cultures
Used 100ng/ml concentration on neonatal rat cardiomyocytes with and without FBS in DMEM medium. Able to show binding affinity to FGF-16 receptors and subcellular signaling pathway activation. Great product.
From:  Jie | Date:  27.08.2020