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Recombinant Human GDF-7

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Product Details

Catalogue Number: 120-37
Description:

GDF-7 belongs to the TGF-β superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissues. Recombinant Human GDF-7 is a 28.0 kDa disulfide-linked homodimer containing two 129 amino acid residues.

Source: E.coli

Synonyms: Growth/Differentiation Factor-7, BMP-12

AA Sequence (monomer): TALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.

Calculated Molecular Weight: 28 kDa

Accession Number: Q7Z4P5

Gene ID: 151449

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Armandari, I
Title
CREB signaling activity correlates with differentiation and survival in medulloblastoma
Citation
Scientific Reports; 11(1) pg16077
PubMed Id
First Author
Boisvert, E M
Title
The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells.
Citation
Scientific Reports; 5 pg16821
PubMed Id