Wachstumsfaktoren & Zytokine

Recombinant Human IFN-α (2a)

0 ReviewsSubmit a Review

Product Details

Catalogue Number: 300-02AA
Description:
Recombinant Human IFN-α (2a)

Proteins of this family play an important role in inducing non‐specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFNα is an acid stable molecule that signals through IFNα/βR, which is also used by IFN‐β. Both IFNs have similar anti‐viral activity and regulate expression of MHC class I antigens. IFN‐α contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant Human IFN‐α (2a) is a 19.3 kDa protein containing 166 amino acid residues.

Source: E.coli

Synonyms: Interferon alpha‐2, Interferon alpha A, Type I interferon

AA Sequence: MCDLPQTHSL GSRRTLMLLA QMRKISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cytotoxicity assay using human TF-1 cells.

Recombinant Human IFN-alpha Biological Activity Graph Recombinant Human IFN-alpha Biological Activity Graph

Calculated Molecular Weight: 19.3 kDa

Accession Number: P01563

Gene ID: 3440

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Country Of Origin: USA

Not for human use.

Research Interest