Recombinant Human IL-8 (CXCL8) (77 a.a.) 0 ReviewsSubmit a Review Product Details Catalogue Number: 200-08 Description: IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant Human IL-8 (CXCL8) (77 a.a.) (endothelial-derived) is an 8.9 kDa protein containing 77 amino acid residues. Source: E.coli Synonyms: Interleukin-8, CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1 AA Sequence: AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 25.0-150.0 ng/ml. Calculated Molecular Weight: 8.9 kDa Accession Number: P10145 Gene ID: 3576 crossreactivity: Bacteria, Chicken, Human, Mouse, Pig References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Apoptosis Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy Transplantation product.subtitle.recentcitations First Author Zhang, Y Title A new antagonist for CCR4 attenuates allergic lung inflammation in a mouse model of asthma. Citation Scientific Reports; 7(1) pg15038 PubMed Id 29118379 First Author Subramanian, B C Title The LTB4-BLT1 axis regulates actomyosin and β2-integrin dynamics during neutrophil extravasation. Citation The Journal of Cell Biology; 219(10) PubMed Id 32854115 First Author Su, S Title Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages. Citation Cell; 175(2) pg442-457.e23 PubMed Id 30290143
