Chemokine

Recombinant Human LD78β (CCL3L1)

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Product Details

Catalogue Number: 300-56
Description:

LD78β is a CC chemokine that is closely related to MIP-1α. It signals through the CCR5 receptor and the β-chemokine receptor, D6. LD78β has been shown to exhibit potent activity in HIV suppression assays. Recombinant Human LD78β is a 7.7 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: CCL3L1

AA Sequence: APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract mouse BaF3 cells expressing the CCR5 receptor using a concentration range of 5.0-25.0 ng/ml.

Calculated Molecular Weight: 7.7 kDa

Accession Number: P16619

Gene ID: 6349

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Singh, K
Title
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
Citation
Scientific Reports; 7(1) pg4267
PubMed Id
First Author
Alenazi, Y
Title
Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.
Citation
Scientific Reports; 8(1) pg6333
PubMed Id
First Author
Lee, A W
Title
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
Citation
The Journal of Biological Chemistry; 294(29) pg11199-11212
PubMed Id