LD78β is a CC chemokine that is closely related to MIP-1α. It signals through the CCR5 receptor and the β-chemokine receptor, D6. LD78β has been shown to exhibit potent activity in HIV suppression assays. Recombinant Human LD78β is a 7.7 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA
≥ 98% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to chemoattract mouse BaF3 cells expressing the CCR5 receptor using a concentration range of 5.0-25.0 ng/ml.
Calculated Molecular Weight:
Not for human use.