Recombinant Human MCP-3 (CCL7) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-17 Description: The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-3 is a 9.0 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. Source: E.coli Synonyms: Monocyte Chemotactic Protein-3, CCL7, MARC AA Sequence: QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 9 kDa Accession Number: P80098 Gene ID: 6354 crossreactivity: Bacteria, Hamster, Human, Human + Rat, Monkey, Mouse, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Cancer Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy product.subtitle.recentcitations First Author Westermann, D Title Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy. Citation Circulation; 124(19) pg2082-93 PubMed Id 21986287 First Author Bodaghi, B Title Chemokine sequestration by viral chemoreceptors as a novel viral escape strategy: withdrawal of chemokines from the environment of cytomegalovirus-infected cells. Citation The Journal of Experimental Medicine; 188(5) pg855-66 PubMed Id 9730887 First Author Van den Steen, P E Title The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors. Citation The Journal of Biological Chemistry; 281(27) pg18626-37 PubMed Id 16672230
