Chemokine

Recombinant Human TARC (CCL17)

Product Details

Catalogue Number: 300-30
Description:

TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus, and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant Human TARC is an 8.0 kDa protein containing 71 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Thymus and Activation Regulated Chemokine, CCL17, ABCD-2

AA Sequence: ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human T cells using a concentration range of 1.0-10.0 ng/ml.

Calculated Molecular Weight: 8 kDa

Accession Number: Q92583

Gene ID: 6361

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Struyf, S
Title
Enhanced anti-HIV-1 activity and altered chemotactic potency of NH2-terminally processed macrophage-derived chemokine (MDC) imply an additional MDC receptor.
Citation
Journal of immunology (Baltimore, Md. : 1950); 161(6) pg2672-5
PubMed Id
First Author
Hamada, T
Title
Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation.
Citation
The Journal of Experimental Medicine; 188(3) pg539-48
PubMed Id
First Author
Schaniel, C
Title
Activated murine B lymphocytes and dendritic cells produce a novel CC chemokine which acts selectively on activated T cells.
Citation
The Journal of Experimental Medicine; 188(3) pg451-63
PubMed Id