Chemokine

Recombinant Human TECK (CCL25)

Product Details

Catalogue Number: 300-45
Description:

TECK is a CC chemokine, specifically expressed by thymic stromal cells, and signals through the CCR9 receptor. TECK is chemotactic towards activated macrophages, thymocytes and dendritic cells. Recombinant Human TECK is a 14.2 kDa protein containing 127 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Thymus Expressed Chemokine

AA Sequence: QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSKRNVSLL ISANSGL

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to bind CCR9 receptor expressed on the surface of MOLT4 cells.

Calculated Molecular Weight: 14.2 kDa

Accession Number: O15444

Gene ID: 6370

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Fu, Y
Title
CD27-CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression.
Citation
Cell Reports; 36(2) pg109344
PubMed Id
First Author
Blokland, S L
Title
Decreased circulating CXCR3 + CCR9+T helper cells are associated with elevated levels of their ligands CXCL10 and CCL25 in the salivary gland of patients with Sjögren's syndrome to facilitate their concerted migration.
Citation
Scandinavian Journal Of Immunology; 91(3) pge12852
PubMed Id
First Author
Joutoku, Z
Title
CCL21/CCR7 axis regulating juvenile cartilage repair can enhance cartilage healing in adults.
Citation
Stem Cell Reports; 9(1) pg5165
PubMed Id

product.subtitle.productreviews

Existing reviews
works as expected
Our lab appreciates the fast delivery, careful packaging and products quality. We purchase cytokines regularly and this one to works as expected. High quality and reliable for consistent results.
From:  Ioana | Date:  26.08.2020