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Recombinant Human TFF-1

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Product Details

Catalogue Number: 300-60
Description:


Recombinant Human TFF-1

The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF1 is essential for normal differentiation of the antral and pyloric gastric mucosa, and functions as a gastric-specific tumor suppressor gene. Recombinant Human TFF-1 is a 6.7 kDa monomeric protein consisting of a 60 amino acid polypeptide chain, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.

Source: E.coli

Synonyms: Trefoil Factor 1 (TFF1), pS2 protein, HP1.A, Breast Cancer Estrogen-Inducible protein (BCEI), PNR2

AA Sequence: EAQTETCTVA PRERQNCGFP GVTPSQCANK GCCFDDTVRG VPWCFYPNTI DVPPEEECEF

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human MCF-7 cells using a concentration 5-10 μg/ml.

Calculated Molecular Weight: 6.7 kDa

Accession Number: P04155

Gene ID: 7031

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Radiloff, D R
Title
Trefoil factor 1 acts to suppress senescence induced by oncogene activation during the cellular transformation process.
Citation
Proceedings of the National Academy of Sciences of the United States of America; 108(16) pg6591-6
PubMed Id