Chemokine

Recombinant Murine BCA-1/BLC (CXCL13)

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Product Details

Catalogue Number: 250-24
Description:

BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor, CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes, and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Murine BLC is a 9.8 kDa protein containing 88 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.

Source: E.coli

Synonyms: B cell Attracting Chemokine-1, CXCL13, BLC (mouse), BLR1 Ligand

AA Sequence: ILEAHYTNLK CRCSGVISTV VGLNIIDRIQ VTPPGNGCPK TEVVIWTKMK KVICVNPRAK WLQRLLRHVQ SKSLSSTPQA PVSKRRAA

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human B cells.

Calculated Molecular Weight: 9.8 kDa

Accession Number: O55038

Gene ID: 55985

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Wu, X
Title
CXCL13/CXCR5 enhances sodium channel Nav1.8 current density via p38 MAP kinase in primary sensory neurons following inflammatory pain.
Citation
Scientific Reports; 6 pg34836
PubMed Id
First Author
Ma, L
Title
ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.
Citation
The Journal of Experimental Medicine; 218(12)
PubMed Id
First Author
Kara, E E
Title
Atypical chemokine receptor 4 shapes activated B cell fate.
Citation
The Journal of Experimental Medicine; 215(3) pg801-813
PubMed Id