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Recombinant Murine EGF

Product Details

Catalogue Number: 315-09
Description:
Recombinant Murine EGF

EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant Murine EGF is a 6.0 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide bonds.

Source: E.coli

Synonyms: Epidermal Growth Factor, Urogastrone, URG

AA Sequence: NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

Calculated Molecular Weight: 6 kDa

Accession Number: P01132

Gene ID: 13645

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Sakuma, R
Title
Brain Pericytes Acquire Stemness via the Nrf2-Dependent Antioxidant System.
Citation
Stem cells (Dayton, Ohio); 40(7) pg641-654
PubMed Id
First Author
Tsubakihara, Y
Title
TGFβ selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition.
Citation
Molecular Oncology; 16(12) pg2330-2354
PubMed Id
First Author
Cambuli, F
Title
Intra-epithelial non-canonical Activin A signaling safeguards prostate progenitor quiescence.
Citation
EMBO reports; 23(5) pge54049
PubMed Id

product.subtitle.productreviews

Existing reviews
EGF
Works well for cell culture
From:  Yu | Date:  11.07.2020
Helps grow patient derived stem cells
Extremely helpful in keeping the stem cell characteristics of patient-derived stem cells unchanged.
From:  Shrita | Date:  26.08.2020
Organoid Media supplement growth factor
We have been using this product in our lab as a supplement in the media for growing organoids derived from a mouse prostate. It is a really helpful product and helps for the 3D organoids to form isolated from the epithelial tissue of the mouse prostate. The delivery of the product is also very quick and that's why we prefer buying it from peprotech.
From:  Tejasveeta | Date:  27.08.2020
Quality product - no other match!
We routinely use recombinant EGF for maintaining our brain cancer cells. There is no match for the quality that Peprotech provides. Even after their move to a different location or during this pandemic the supply did not interrupt. That helped us to keep our research going! Keep it up!
From:  Munjal | Date:  28.08.2020