Wachstumsfaktoren & Zytokine

Recombinant Murine FGF-basic

Product Details

Catalogue Number: 450-33
Description:

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Murine FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin

AA Sequence: PALPEDGGAA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHV KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTEE CFFFERLESN NYNTYRSRKY SSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.

Calculated Molecular Weight: 16.3 kDa

Accession Number: P15655

Gene ID: 14173

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Bijman, J T
Title
In vitro proliferation of primary human head and neck squamous cell carcinomas evaluated by flow cytometry.
Citation
Cancer Letters; 36(1) pg71-81
PubMed Id
First Author
Meng, Y
Title
Hexokinase 2-driven glycolysis in pericytes activates their contractility leading to tumor blood vessel abnormalities
Citation
Nature Communications; 12(1) pg6011
PubMed Id
First Author
Dignum, T
Title
Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo.
Citation
Cell Reports; 36(11) pg109675
PubMed Id

product.subtitle.productreviews

Existing reviews
Perfect for mouse neural stem cells
We use recombinant murine FGF to maintain mouse neural stem cells. Quite important for the primary neural stem cell culture after isolation from the fresh tissues. We do not have to worry given Peprotech's quality.  Even during this pandemic, the supply did not interrupt. That helped us to keep our research going! Keep it up!
From:  Munjal | Date:  28.08.2020