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Chemokine

Recombinant Murine I-TAC (CXCL11)

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Produktdetails

Katalognummer: 250-29
Beschreibung:
Recombinant Murine I-TAC (CXCL11)

I-TAC is a "non-ELR" CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2-activated T cells, but does not affect freshly isolated un-stimulated T cells, neutrophils, or monocytes. Recombinant Murine I-TAC is a 9.0 kDa protein containing 79 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines.

Source: E.coli

Synonyms: Interferon Inducible T-Cell α Chemokine, CXCL11, B-R1

AA Sequence: FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRRQNM

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract murine CXCR3-transfected HEK293 cells using a concentration range of 10.0-100.0 ng/ml.

Recombinant Murine I-TAC (CXCL11) Biological Activity Graph

Calculated Molecular Weight: 9 kDa

Accession Number: Q9JHH5

Gene ID: 56066

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

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Erstautor
He, H
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Aging-induced IL27Ra signaling impairs hematopoietic stem cells.
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Blood; 136(2) pg183-198
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Joutoku, Z
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CCL21/CCR7 axis regulating juvenile cartilage repair can enhance cartilage healing in adults.
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Stem Cell Reports; 9(1) pg5165
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Ishihara, J
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Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
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Nature Communications; 9(1) pg2163
PubMed ID