Recombinant Murine IL-7 2 ReviewsSubmit a Review Product Details Catalogue Number: 217-17 Description: IL-7 is a hematopoietic growth factor that primarily affects early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2. Human and murine IL-7 are cross-species reactive. Recombinant Murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues. Source: E.coli Synonyms: Lymphopoietin 1(LP-1), pre-B cell factor AA Sequence: MECHIKDKEG KAYESVLMIS IDELDKMTGT DSNCPNNEPN FFRKHVCDDT KEAAFLNRAA RKLKQFLKMN ISEEFNVHLL TVSQGTQTLV NCTSKEEKNV KEQKKNDACF LKRLLREIKT CWNKILKGSI Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg. Calculated Molecular Weight: 15 kDa Accession Number: P10168 Gene ID: 16196 Note: 1mg will be provided as 2x500μg. crossreactivity: Human, Mouse, Mouse + Human References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest CAR T Cell Cancer Immune System Inflammation Stem Cells & Differentiation product.subtitle.recentcitations First Author Kauts, M Title Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells. Citation Stem Cell Reports; 11(4) pg1009-1020 PubMed Id 30197119 First Author Rochman, Y Title Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7-induced signaling. Citation Proceedings of the National Academy of Sciences of the United States of America; 107(45) pg19455-60 PubMed Id 20974963 First Author Lai, D Title KLF13 sustains thymic memory-like CD8(+) T cells in BALB/c mice by regulating IL-4-generating invariant natural killer T cells. Citation The Journal of Experimental Medicine; 208(5) pg1093-103 PubMed Id 21482696 product.subtitle.productreviews Existing reviews Works everytime Happy to use this cytokine. Very efficient and economically priced. The product comes with all the relevant information and protocols on handling. Very helpful for expanding T cells and during ACT experiments. From: Vineet | Date: 10.08.2020 × Works everytime Happy to use this cytokine. Very efficient and economically priced. The product comes with all the relevant information and protocols on handling. Very helpful for expanding T cells and during ACT experiments. From: Vineet | Date: 10.08.2020 Close Great pro-survival cytokine for mouse T cells We routinely use this great cytokine to generate mouse memory CD8+ T cells and also keep naive T cells alive. The pricing and consistency of this cytokine can't be beat. From: Chirag | Date: 31.08.2020 × Great pro-survival cytokine for mouse T cells We routinely use this great cytokine to generate mouse memory CD8+ T cells and also keep naive T cells alive. The pricing and consistency of this cytokine can't be beat. From: Chirag | Date: 31.08.2020 Close
