Chemokine

Recombinant Murine MIP-2 (CXCL2)

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Product Details

Catalogue Number: 250-15
Description:

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine MIP-2 is a 7.8 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-2α, MIP-2α, Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAβ), CXCL2, GRO2

AA Sequence: AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml.

Calculated Molecular Weight: 7.8 kDa

Accession Number: P10889

Gene ID: 20310

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Liou, G
Title
Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs.
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The Journal of Cell Biology; 202(3) pg563-77
PubMed Id
First Author
Kim, S Y
Title
Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.
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The Journal of Biological Chemistry; 281(39) pg28794-801
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First Author
Gilbert, L A
Title
DNA damage-mediated induction of a chemoresistant niche.
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Cell; 143(3) pg355-66
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