Chemokine

Recombinant Murine MIP-3β (CCL19)

Product Details

Catalogue Number: 250-27B
Description:
Recombinant Murine MIP-3β (CCL19)

MIP-3β is a CC chemokine, expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells that signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant Murine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-3β, CCL19, ELC, Exodus-3, SCYA19

AA Sequence: GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract activated human T cells expressing the CCR7 receptor. The ED50 for this effect is 30-90 ng/ml.

Calculated Molecular Weight: 9.2 kDa

Accession Number: O70460

Gene ID: 24047

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Tse, B C
Title
Exposure to Systemic Immunosuppressive Ultraviolet Radiation Alters T Cell Recirculation through Sphingosine-1-Phosphate.
Citation
Journal of immunology (Baltimore, Md. : 1950); 207(9) pg2278-2287
PubMed Id
First Author
Qin, T
Title
Mucosal Vaccination for Influenza Protection Enhanced by Catalytic Immune-Adjuvant.
Citation
Advanced science (Weinheim, Baden-Wurttemberg, Germany); 7(18) pg2000771
PubMed Id
First Author
Cain, D W
Title
Murine Glucocorticoid Receptors Orchestrate B Cell Migration Selectively between Bone Marrow and Blood.
Citation
Journal of immunology (Baltimore, Md. : 1950); 205(3) pg619-629
PubMed Id

product.subtitle.productreviews

Existing reviews
migration assays
works well for dendritic cells in migration assays!
From:  Caitlin | Date:  13.07.2020