Recombinant Murine MIP-3α (CCL20) 0 BewertungenSubmit a Review Produktdetails Katalognummer: 250-27 Beschreibung: MIP-3α is a CC chemokine, expressed in the liver, lymph nodes, appendix, PBL and lungs that can signal through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells, and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant Murine MIP-3α is a 7.9 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: Macrophage Inflammatory Protein-3α, CCL20, LARC, Exodus-1 AA Sequence: ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract murine CCR6-transfected HEK293 cells using a concentration range of 0.1-10.0 ng/ml Calculated Molecular Weight: 7.9 kDa Accession Number: O89093 Gene ID: 20297 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Human + Mouse, Mouse References PubMed SDS Datenblattsuche Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations Erstautor Yagawa, Y Titel Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy. Literaturstelle Scientific Reports; 7(1) pg15996 PubMed ID 29167448 Erstautor Singh, K Titel Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Literaturstelle Scientific Reports; 7(1) pg4267 PubMed ID 28655871 Erstautor Velázquez, F Titel CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo. Literaturstelle Journal of immunology (Baltimore, Md. : 1950); 196(3) pg1305-1316 PubMed ID 26700769
