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Recombinant Rat GM-CSF

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Product Details

Catalogue Number: 400-23
Description:
Recombinant Rat GM-CSF

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages, and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acid residues.

Source: E.coli

Synonyms: Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α

AA Sequence: MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Murine FDC-P1 cells is ≤ 0.01 ng/ml, corresponding to a specific activity of ≥ 1 x 108 units/mg.

Calculated Molecular Weight: 14.5 kDa

Accession Number: P48750

Gene ID: 116630

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Prendecki, M
Title
Glomerulonephritis and autoimmune vasculitis are independent of P2RX7 but may depend on alternative inflammasome pathways.
Citation
The Journal of Pathology; 257(3) pg300-313
PubMed Id
First Author
Ku, M W
Title
Lentiviral vector induces high-quality memory T cells via dendritic cells transduction.
Citation
Communications Biology; 4(1) pg713
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First Author
Stangl, H
Title
MHC/class-II-positive cells inhibit corticosterone of adrenal gland cells in experimental arthritis: a role for IL-1β, IL-18, and the inflammasome
Citation
Scientific Reports; 10(1) pg17071
PubMed Id