Recombinant Rat GRO-β/MIP-2 (CXCL2)

Product Details

Catalogue Number: 400-11

Description:

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Rat GRO-β/MIP-2 is a 7.9 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Source: E.coli

Synonyms: Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAβ), CXCL2, Macrophage Inflammatory Protein-2, MIP-2α, GRO2

AA Sequence: VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 7.9 kDa

Accession Number: P30348

Gene ID: 114105

crossreactivity:

Human, Mouse, Rat

Country Of Origin: USA

Not for human use.

Research Interest

Angiogenesis/Cardiovascular

product.subtitle.recentcitations

First Author

McWilliam, A S

Title

Dendritic cells are recruited into the airway epithelium during the inflammatory response to a broad spectrum of stimuli.

Citation

The Journal of Experimental Medicine; 184(6) pg2429-32

PubMed Id

8976199

First Author

Abu-Taha, M

Title

Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.

Citation

Journal of immunology (Baltimore, Md. : 1950); 183(2) pg1393-402

PubMed Id

19553526

First Author

Mateo, T

Title

A critical role for TNFalpha in the selective attachment of mononuclear leukocytes to angiotensin-II-stimulated arterioles.

Citation

Blood; 110(6) pg1895-902

PubMed Id

17595330

Chemokine