Recombinant Rat GRO-β/MIP-2 (CXCL2) 0 ReviewsSubmit a Review Product Details Catalogue Number: 400-11 Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Rat GRO-β/MIP-2 is a 7.9 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2. Source: E.coli Synonyms: Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAβ), CXCL2, Macrophage Inflammatory Protein-2, MIP-2α, GRO2 AA Sequence: VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 7.9 kDa Accession Number: P30348 Gene ID: 114105 crossreactivity: Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing product.subtitle.recentcitations First Author Nabah, Y N Title Angiotensin II induces neutrophil accumulation in vivo through generation and release of CXC chemokines. Citation Circulation; 110(23) pg3581-6 PubMed Id 15569833 First Author Trettel, F Title Ligand-independent CXCR2 dimerization. Citation The Journal of Biological Chemistry; 278(42) pg40980-8 PubMed Id 12888558 First Author Limatola, C Title The growth-related gene product beta induces sphingomyelin hydrolysis and activation of c-Jun N-terminal kinase in rat cerebellar granule neurones. Citation The Journal of Biological Chemistry; 274(51) pg36537-43 PubMed Id 10593952
