Small Molecules

Biogems

SAG

Produktdetails

Katalognummer: 9128694
Beschreibung:

SAG is a cell-permeable agonist for smoothened, a key part of the hedgehog signaling pathway. It directly activates smoothened and can prevent cyclopamine inhibition. SAG can be used to enhance the neuronal differentiation of human induced pluripotent stem cells and aid in the survival and proliferation of neuronal precursors. It is reported to prevent drug induced brain injury and stimulate normal cerebellum after injection in mice with an induced Down’s syndrome-like condition.

Synonyms: AC1NR49D, CHEMBL1221983

Application:

Formulation:
Crystalline solid
Chemical Name:
3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide
Molecular Formula:

C28H28ClN3OS

Molecular Weight:
490.1
CAS Number:
912545-86-9
Purity:
≥98%

Note:

Product supplied by Biogems

Research Interest

Country Of Origin: USA

Not for human use.