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Recombinant Human/Rat Neuritin

Catalog Number:
450-36D
Synonyms:
CPG15, NRN1
Description:
Neuritin is a neurotrophic factor that is expressed in response to the induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system, and in neuronal structures related to synaptic plasticity in the adult nervous system.   Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation.   Recombinant Human/Rat Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.72 kDa polypeptide monomers, each containing 88 amino acid residues.
AA Sequence:
AGKCDAVFKG FSDCLLKLGD SMANYPQGLD DKTNIKTVCT YWEDFHSCTV TALTDCQEGA KDMWDKLRKE SKNLNIQGSL FELCGSGN
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/ml.
Cross Reactivity:
Rat
Research Interests:
Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.
Purchase This Product
  Size Price Qty
A 5µg 80.00 USD
B 20µg 195.00 USD
100µg 600.00 USD
250µg 1,050.00 USD
500µg 1,800.00 USD
1mg 3,000.00 USD
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