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Proliferation Research

Proliferation is defined as the highly regulated cascade of events responsible for cellular reproduction and maintenance of the relationship between rates of cellular death and division within an expanding population of similar cells.  Controlled and regulated proliferation of specific target cells is essential for a broad spectrum of physiological processes including fertilization, prenatal and postnatal development, and tissue maintenance and repair.  Numerous biological mechanisms have evolved to ensure proper regulation and progression of these processes.  Although these safeguards function to ensure the identification, prevention, and rectification of abnormal progression through the phases of cellular division, unmitigated proliferation can be provoked by instances of spontaneous genomic mutations or those mutations resulting from physical or chemical mutagens.  Unrestrained cell proliferation that defies the normal constraints of cellular division is one of the defining characteristics of cancer, in which a culmination of mutations or other aberrations of cellular processes ultimately lead to decreased density-dependent growth inhibition, anchorage-independence, telomerase production, decreased dependence on external growth factors, inhibition of cell cycle control mechanisms, the inhibition of controlled apoptosis of damaged cells, chromosomal abnormalities, along with the modification of other cellular attributes.  Increased knowledge of both normal and abnormal proliferative mechanisms is essential to the comprehensive understanding of cancer development as well as the functioning of normal developmental processes.

PeproTech continues to offer an assortment of products considered relevant to the research of proliferation; a listing of these products can be found below for your browsing convenience.
Catalog Number: Product Name: Research Interest:
Category: Subcategory: Is New:
NewProduct Name Catalog NumberSubcategory SizePrice
PeproGMP® Recombinant Human EGFGMP100-15GMP CytokinesA
B
100µg
500µg
450.00 USD
1,000.00 USD
PeproGMP® Recombinant Human FGF-basicGMP100-18BGMP CytokinesA
B
25µg
100µg
240.00 USD
720.00 USD
PeproGMP® Recombinant Human Flt3-LigandGMP300-19GMP CytokinesA
B
50µg
100µg
870.00 USD
1,450.00 USD
PeproGMP® Recombinant Human IL-3GMP200-03GMP CytokinesA
B
50µg
100µg
775.00 USD
1,450.00 USD
PeproGMP® Recombinant Human SCFGMP300-07GMP CytokinesA
B
50µg
100µg
775.00 USD
1,450.00 USD
PeproGMP® Recombinant Human TPOGMP300-18GMP CytokinesA
B
50µg
100µg
1,050.00 USD
1,750.00 USD
Recombinant Human 4-1BB Receptor310-15Growth Factors & CytokinesA
B
5µg
20µg
100µg
1mg
80.00 USD
195.00 USD
600.00 USD
3,000.00 USD
Recombinant Human BAFF Receptor310-13RGrowth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Human BMP-3120-24BGrowth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Murine BMP-4315-27Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human BMP-6120-06Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD
Recombinant Human BMP-7120-03Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,560.00 USD
7,800.00 USD
Recombinant Human BMP-10120-40Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human BMP-13/CDMP-2120-04Growth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Human/Murine/Rat BMP-2 (CHO cell derived)120-02CGrowth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD
Recombinant Human/Murine/Rat BMP-2 (E.coli derived)120-02Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human BMP-4 (E.coli derived)120-05ETGrowth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human BMP-4 (HeLa cell derived)120-05Growth Factors & CytokinesA
B
1µg
5µg
100µg
1mg
80.00 USD
195.00 USD
1,200.00 USD
7,000.00 USD
Recombinant Human BMP-7120-03PGrowth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD
Recombinant Human sCD40 Ligand310-02Growth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD