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TGF-β Superfamily Research

Encompassing a plethora of growth, differentiation and morphogenic factors, the Transforming Growth Factor-β (TGF-β) Superfamily is comprised of signaling proteins that have been universally conserved throughout the animal kingdom and presently consists of over forty members, the likes of which include:  TGF-β isoforms, bone morphogenetic proteins (BMPs), growth differentiation factors (GDFs), activins, and inhibins.  Considered vital to the modulation of cell proliferation, differentiation, matrix synthesis, and apoptosis, members of the TGF-β Superfamily are fundamental to prenatal development and the postnatal growth, remodeling, and maintenance of various tissues and organs.  Noted for activating Smad signaling cascades through interactions with a conserved family of cell surface serine/threonine-specific protein kinase receptors, the complexity of TGF-β signaling has been demonstrated through the additional regulation of physiological processes by TGF-β Superfamily Ligand through non-canonical pathways, and the activation of signaling molecules other than Smad proteins.  Given the intricacies and significance associated with the activities of TGF-β Superfamily proteins, the impairment of proper signaling has been understandably connected to a variety of clinical indications, such as tumor cell growth, fibrosis, skeletal defects, and autoimmune disease.  Therefore, understanding the regulatory mechanisms that control TGF-β signaling, as well as the identification and characterization of their molecular components, have become topics of intense investigation.

PeproTech continues to offer an assortment of products considered relevant to the research of the TGF-β Superfamily; a listing of these products can be found below for your browsing convenience.
Catalog Number: Product Name: Research Interest:
Category: Subcategory: Is New:
NewProduct Name Catalog NumberSubcategory SizePrice
Recombinant Human /Murine/Rat Activin A (E.coli derived)120-14EGrowth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human/Murine/Rat Activin A (CHO cell derived)120-14PGrowth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD
Recombinant Human/Murine/Rat Activin A (Insect derived)120-14Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,200.00 USD
6,500.00 USD
Recombinant Human Activin B120-15Growth Factors & CytokinesA
B
1µg
5µg
100µg
1mg
80.00 USD
195.00 USD
1,960.00 USD
9,800.00 USD
Recombinant Human BMP-3120-24BGrowth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Murine BMP-4315-27Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human BMP-5120-39Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human BMP-6120-06Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD
Recombinant Human BMP-7120-03Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,560.00 USD
7,800.00 USD
Recombinant Human BMP-10120-40Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human BMP-13/CDMP-2120-04Growth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Human/Murine/Rat BMP-2 (CHO cell derived)120-02CGrowth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD
Recombinant Human/Murine/Rat BMP-2 (E.coli derived)120-02Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human BMP-4 (E.coli derived)120-05ETGrowth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human BMP-4 (HeLa cell derived)120-05Growth Factors & CytokinesA
B
1µg
5µg
100µg
1mg
80.00 USD
195.00 USD
1,200.00 USD
7,000.00 USD
Recombinant Human BMP-7120-03PGrowth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD
Recombinant Human GASP-1120-41Growth Factors & CytokinesA
B
5µg
25µg
100µg
1mg
80.00 USD
195.00 USD
750.00 USD
3,900.00 USD
Recombinant Human GDF-2120-07Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD
Recombinant Human GDF-3120-22Growth Factors & CytokinesA
B
5µg
20µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human GDF-5 (BMP-14/CDMP-1)120-01Growth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD