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TNF Superfamily Research

Recognized for their involvement in the regulation of a broad spectrum of biological processes, such as cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation, members of the Tumor Necrosis Factor (TNF) Superfamily were originally identified as necrosis-inducing, anti-tumor cytokines for their ability to cause cell death in sarcomas and other cancerous cells.  The members of the TNF Superfamily are responsible for the regulation of cellular differentiation, survival and death through the activation of multiple signal transduction pathways by ligand mediated trimerization and the resulting recruitment of several intracellular adaptors.  Although normal levels of activity can be pivotal in terms of cellular growth and regeneration, as well as regulated events of apoptosis and inflammatory response, accumulating evidence indicates that the uncontrolled synthesis of TNF Superfamily proteins can be linked to a number of human diseases and disorders of chronic inflammation, as well as autoimmune diseases, insulin resistance, and cancer.  Consequently, a great deal of interest surrounds the understanding of those pathways associated with the activity of TNF Superfamily cytokines and the development of therapeutic methods of inhibition and regulation of TNF activity, release, translation and transcription.

PeproTech continues to offer an assortment of products considered relevant to research related to members of the TNF Superfamily; a listing of these products can be found below for your browsing convenience.
Catalog Number: Product Name: Research Interest:
Category: Subcategory: Is New:
NewProduct Name Catalog NumberSubcategory SizePrice
Recombinant Human 4-1BB Ligand310-11Growth Factors & CytokinesA
B
5µg
20µg
100µg
1mg
80.00 USD
195.00 USD
600.00 USD
3,000.00 USD
Recombinant Human 4-1BB Receptor310-15Growth Factors & CytokinesA
B
5µg
20µg
100µg
1mg
80.00 USD
195.00 USD
600.00 USD
3,000.00 USD
Recombinant Human AITRL310-22Growth Factors & CytokinesA
B
5µg
20µg
100µg
1mg
80.00 USD
195.00 USD
850.00 USD
5,200.00 USD
Recombinant Human APRIL310-10CGrowth Factors & CytokinesA
B
2µg
10µg
80.00 USD
195.00 USD
Recombinant Murine APRIL315-13Growth Factors & CytokinesA
B
5µg
20µg
100µg
1mg
80.00 USD
195.00 USD
600.00 USD
3,000.00 USD
Recombinant Human BAFF310-13Growth Factors & CytokinesA
B
5µg
20µg
100µg
1mg
80.00 USD
195.00 USD
850.00 USD
5,200.00 USD
Recombinant Human BAFF Receptor310-13RGrowth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Human BCMA310-16Growth Factors & CytokinesA
B
5µg
20µg
100µg
1mg
80.00 USD
195.00 USD
850.00 USD
5,200.00 USD
Recombinant Human sCD27 Ligand310-30Growth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Human sCD40 Ligand310-02Growth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Murine sCD40 Ligand315-15Growth Factors & CytokinesA
B
5µg
25µg
100µg
1mg
80.00 USD
195.00 USD
600.00 USD
3,000.00 USD
Recombinant Human sFas Ligand310-03HGrowth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
860.00 USD
4,300.00 USD
Recombinant Human sFas Receptor310-20Growth Factors & CytokinesA
B
5µg
20µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human HVEM-Fc310-27Growth Factors & CytokinesA
B
20µg
100µg
200µg
1mg
80.00 USD
195.00 USD
330.00 USD
1,100.00 USD
Recombinant Murine LIGHT315-12Growth Factors & CytokinesA
B
5µg
20µg
100µg
1mg
80.00 USD
195.00 USD
600.00 USD
3,000.00 USD
Recombinant Human OPG450-14Growth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Human sOX40 Ligand310-28Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD
Recombinant Human sRANK Ligand310-01Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD
Recombinant Murine sRANK Ligand315-11Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD
Recombinant Rat sRANK Ligand400-30Growth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
1,040.00 USD
5,200.00 USD