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Wound Healing Research

Wound healing is the complex, dynamic process of restoration by which cellular structure and tissue arrangement are re-established following an incident of injury through a complex and highly coordinated series of interconnected events.  Generally, the process of wound healing is divided into four sequential, yet overlapping phases: the hemostasis phase, the inflammatory phase, the proliferative phase and the remodeling phase.  Homeostasis, the initial phase of wound healing that begins immediately after infliction of an injury, is the process by which blood flow is arrested or stagnated through the aggregation of platelets and the development of a fibrin clot, which in turn provides the structural support for the cellular constituents of inflammation.  The subsequent inflammatory phase is initiated by the release of cytokines from these aggregating platelets, and entails the orchestrated delivery of leukocytes, and later macrophages, for the removal of any injurious stimuli and compromised tissue from the affected region.  This phase concludes with the secretion of numerous factors responsible for initiating the migration and division of those cells destined for involvement in the proliferative phase.  This third phase of wound healing is characterized by the formation of new blood vessels (angiogenesis), the excretion of collagen and fibronectin from a newly forming extracellular matrix, the proliferation and migration of epithelial cells, and wound contraction.  Wound healing concludes with the fourth and final phase of remodeling.  During remodeling, which can persist for many years following the initial incident of injury, the wound enters a state of constant alteration during which wound contraction progresses, superfluous cells are removed through apoptosis, and collagen is remodeled and deposited along tension lines.  Under normal circumstances wound healing progresses through these four stages in a predictable and timely manner, culminating in the removal of any harmful agents and the replacement of normal skin to once again form a protective barrier against the external environment.  However, the wound healing process is as fragile as it is complex, and it is therefore extremely susceptible to occurrences of dysfunction, which can result in instances of chronic wounds or pathological scarring.

PeproTech continues to offer an assortment of products considered relevant to the research of wound healing; a listing of these products can be found below for your browsing convenience.
Catalog Number: Product Name: Research Interest:
Category: Subcategory: Is New:
NewProduct Name Catalog NumberSubcategory SizePrice
PeproGMP® Recombinant Human EGFGMP100-15GMP CytokinesA
B
100µg
500µg
450.00 USD
1,000.00 USD
PeproGMP® Recombinant Human FGF-basicGMP100-18BGMP CytokinesA
B
25µg
100µg
240.00 USD
720.00 USD
PeproGMP® Recombinant Human IL-6GMP200-06GMP CytokinesA
B
10µg
100µg
290.00 USD
1,450.00 USD
PeproGMP® Recombinant Human TPOGMP300-18GMP CytokinesA
B
50µg
100µg
1,050.00 USD
1,750.00 USD
Recombinant Human Amphiregulin100-55BGrowth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Human sCD28 Fc310-34Growth Factors & CytokinesA
B
20µg
100µg
500µg
1mg
80.00 USD
195.00 USD
660.00 USD
1,100.00 USD
Recombinant Human CTGF120-19Growth Factors & CytokinesA
B
5µg
20µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human CTLA-4 Fc310-05Growth Factors & CytokinesA
B
50µg
200µg
500µg
1mg
80.00 USD
195.00 USD
480.00 USD
800.00 USD
Animal-Free Recombinant Human EGFAF-100-15Growth Factors & CytokinesA
B
100µg
500µg
1mg
80.00 USD
195.00 USD
250.00 USD
Recombinant Murine EGF315-09Growth Factors & CytokinesA
B
100µg
500µg
1mg
80.00 USD
195.00 USD
250.00 USD
Recombinant Rat EGF400-25Growth Factors & CytokinesA
B
20µg
100µg
250µg
1mg
80.00 USD
195.00 USD
385.00 USD
1,100.00 USD
Recombinant Human EGF Receptor (EGFR)100-15RGrowth Factors & CytokinesA
B
2µg
10µg
100µg
1mg
80.00 USD
195.00 USD
780.00 USD
3,900.00 USD
Recombinant Human FGF-acidic100-17AGrowth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Murine FGF-acidic450-33AGrowth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Rat FGF-acidic400-29AGrowth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
300.00 USD
1,500.00 USD
Recombinant Murine FGF-basic450-33Growth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
280.00 USD
1,400.00 USD
Recombinant Rat FGF-basic400-29Growth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
280.00 USD
1,400.00 USD
Recombinant Human FGF-10100-26Growth Factors & CytokinesA
B
5µg
25µg
100µg
1mg
80.00 USD
195.00 USD
600.00 USD
3,000.00 USD
Recombinant Human FGF-basic (146 a.a.)100-18CGrowth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
240.00 USD
1,200.00 USD
Recombinant Human FGF-basic (154 a.a.)100-18BGrowth Factors & CytokinesA
B
10µg
50µg
100µg
1mg
80.00 USD
195.00 USD
215.00 USD
800.00 USD