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Small Molecules

Biogems

BIO

Product Details

Catalog Number: 6676296
Description:

BIO is a cell-permeable selective irreversible inhibitor of glycogen synthase kinase-3 (GSK-3). This inhibitory effect is reported to activate the Wnt signaling pathway and promote self-renewal in human and mouse cells. BIO is also useful in the differentiation of cardiomyocytes from human embryonic cells and Induced pluripotent stem cells as well as cellular reprogramming of mouse cell lines into iPS cells.

Synonyms: MLS001074886, SCHEMBL15565919, SMR000568408, 6BIO

Application:

Formulation:
Crystalline solid
Chemical Name:
(3E)-6-bromo-3-[3-(hydroxyamino)indol-2-ylidene]-1H-indol-2-one
Molecular Formula:

C16H10BrN3O2

Molecular Weight:
356.2
CAS Number:
667463-62-9
Purity:
≥98%

Note:

Product supplied by Biogems

Research Interest

Country Of Origin: USA

Not for human use.