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Small Molecules

Biogems

BIRB 796 (Doramapimod)

Product Details

Catalog Number: 2854848
Description:

BIRB 796 is a member of the N-pyrazole-N′-naphthly urea class of p38 MAPK inhibitors that binds to the kinase with slow association and dissociation rates without affecting JNK substrate phosphorylation. The p38 MAP kinase is involved in the production of pro-inflammatory cytokines such as TNF and IL-1. BIRB 796 is reported to be useful in the maintenance of cell lines by inducing self-renewal.

Synonyms: BIRB796

Application:

Formulation:
Crystalline solid
Chemical Name:
1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea
Molecular Formula:

C31H37N5O3

Molecular Weight:
527.7
CAS Number:
285983-48-4
Purity:
≥98%

Note:

Product supplied by Biogems

Research Interest

Country Of Origin: USA

Not for human use.