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Small Molecules

Biogems

Garcinol

Product Details

Catalog Number: 7883034
Description:

Garcinol is a polyisoprenylated benzophenone derivative and a potent inhibitor of histone acetyltransferases (HATs) PCAF and p300. It has been used to inhibit the growth of cancer cell lines and to promote ex vivo expansion of human stem cells. Garcinol also exhibits antioxidative and chelating activity and is reported to induce apoptosis in HeLa cells by downregulating their global gene expression.

Synonyms: Camboginol, CCRIS 9029, CHEMBL502489

Application:

Formulation:
Crystalline solid
Chemical Name:
(1S,3E,5R,7R)-3-[(3,4-dihydroxyphenyl)-hydroxymethylidene]-6,6-dimethyl-5,7-bis(3-methylbut-2-enyl)-1-[(2S)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]bicyclo[3.3.1]nonane-2,4,9-trione
Molecular Formula:

C38H50O6

Molecular Weight:
602.8
CAS Number:
78824-30-3
Purity:
≥95%

Note:

Product supplied by Biogems

Research Interest

Country Of Origin: USA

Not for human use.