LIF is a pleiotrophic factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. While human LIF is active on mouse cells, mouse LIF is not active on human cells due to its inability to bind to the human LIF receptor. Recombinant Human LIF is a 19.7 kDa protein containing 180 amino acids residues, including three disulfide bonds.
•Additional product information and specifications are provided on the Certificate of Analysis.
All of PeproTech's GMP products are manufactured using animal-derived component free materials.
Leukemia Inhibitory Factor, Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor (MLPLI), Interleukin 6 family cytokine
SPLPITPVNA TCAIRHPCHN NLMNQIRSQL AQLNGSANAL FILYYTAQGE PFPNNLDKLC GPNVTDFPPF HANGTEKAKL VELYRIVVYL GTSLGNITRD QKILNPSALS LHSKLNATAD ILRGLLSNVL CRLCSKYHVG HVDVTYGPDT SGKDVFQKKK LGCQLLGKYK QIIAVLAQAF
≥ 98% by SDS-PAGE gel and HPLC analyses.