PeproTech is proud to be able to continue to support you in the midst of unprecedented challenges pertaining to the COVID-19 virus. For more information, click here.

Growth Factors & Cytokines

Recombinant Human BAFF Receptor

Product Details

Catalog Number: 310-13R
Description:

BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in the spleen, lymph nodes, and resting B cells, and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant Human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extracellular portion of the full BAFFR protein.

Source: E.coli

Synonyms: BAFFR, TNFRSF13C, BLyS receptor 3

AA Sequence: MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 2.0-4.0 μg/ml in the presence of 1.0μg/ml of human soluble BAFF.

Calculated Molecular Weight: 7.7 kDa

Accession Number: Q96RJ3

Gene ID: 115650

Cross Reactivity Cited in References: Research Interest

Country Of Origin: USA

Not for human use.