Growth Factors & Cytokines

Recombinant Human Chemerin

Product Details

Catalogue Number: 300-66
Description:

Chemerin is a secreted chemoattractant protein that can signal through the chemokine-like receptor-1 (CMKLR1). It is expressed in various tissues, including white adipose tissue, and circulates in blood as an inactive 143 amino acid precursor protein. Biologically active Chemerin is generated by proteolytic removal of C-terminal residues by several circulating proteases. Chemerin acts as a chemoattractant for cells expressing the CMKLR1 receptor, which includes certain dendritic cells, macrophages, and adipocytes. Recombinant Human Chemerin is a 15.6 kDa protein consisting of 135 amino acid residues.

Source: E.coli

Synonyms: Tazarotene-induced gene 2 (TIG2), RARRES2

AA Sequence: ELTEAQRRGL QVALEEFHKH PPVQWAFQET SVESAVDTPF PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA CIKLGSEDKV LGRLVHCPIE TQVLREAEEH QETQCLRVQR AGEDPHSFYF PGQFA

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human immature dendritic cells using a concentration range of 1.0-100.0 ng/ml.

Calculated Molecular Weight: 15.6 kDa

Accession Number: Q99969

Gene ID: 5919

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Lahvic, J L
Title
Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132.
Citation
Proceedings of the National Academy of Sciences of the United States of America; 115(37) pg9252-9257
PubMed Id