Recombinant Human ENA-78 (CXCL5) (5-78 a.a.)

Product Details

Catalog Number: 300-22

Description:

ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78; ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokines that bind to the CXCR1 and CXCR2 receptors. Recombinant Human ENA-78 is an 8.0 kDa protein consisting of 74 amino acid residues.

Source: E.coli

Synonyms: Epithelial Neutrophil Activating Peptide-78, CXCL5

AA Sequence: AAVLRELRCV CLQTTQGVHP KMISNLQVFA IGPQCSKVEV VASLKNGKEI CLDPEAPFLK KVIQKILDGG NKEN

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration of 5.0-10.0 ng/ml.

Calculated Molecular Weight: 8 kDa

Accession Number: P42830

Gene ID: 6374

Cross Reactivity Cited in References:

Bacteria, Hamster, Mouse

Research Interest

Immune System

Inflammation

Wound Healing

Angiogenesis/Cardiovascular

Country Of Origin: USA

Not for human use.

Products Cited

Cross-Reactivity

Applications

300-11, 300-12, 300-14, 300-20, 200-08M, 300-17, 300-22,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

200-08M, 300-04, 300-22, 300-24,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

250-07, 300-22,

Mouse

in vitro

Products Cited

Cross-Reactivity

Applications

300-11, 300-12, 300-14, 300-16, 300-20, 300-26, 300-29A, 300-31, 300-39, 300-40, 300-41, 300-46, 300-55, 300-57, 200-08M, 300-06, 300-22, 300-28A, 300-47, 300-50,

Bacteria

in vitro

Products Cited

Cross-Reactivity

Applications

100-21, 120-19, 300-01A, 300-22,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

300-34, 300-11, 300-15, 300-29B, 300-46, 300-48, 300-54, 300-08, 300-28A, 300-43, 300-45, 300-31, 300-36A, 300-14, 300-39, 300-55, 300-16, 300-28B, 300-22, 300-44, 300-33, 300-26, 300-38, 300-57, 300-24, 300-40, 300-41, 300-30, 300-12, 300-50, 300-47, 300-29A, 300-35, 300-17, 300-09, 300-56, 300-04, 300-21,

Human

in vitro

250-01, 250-04, 250-06, 250-07, 250-10, 250-11, 250-12, 250-13, 250-15, 250-16, 250-17, 250-18, 250-20A, 250-20B, 250-22, 250-23, 250-24, 250-26, 250-27, 250-27B, 250-28, 250-29, 250-30, 250-32, 250-36, 250-37, 250-39,

Mouse

Binding Assay

Products Cited

Cross-Reactivity

Applications

300-37, 300-04, 300-08, 300-56, 300-09, 300-58, 300-06, 300-17, 300-15, 300-21, 300-24, 300-38, 300-43, 300-44, 300-30, 300-34, 300-29B, 300-29A, 300-35, 300-36A, 300-29, 300-33, 300-48, 300-54, 300-11, 300-39, 300-40, 300-16, 300-22, 300-22B, 300-41, 300-14, 200-08, 300-26, 300-12, 300-46, 300-28A, 300-28B, 300-47, 300-50, 300-55, 300-31,

Human

Chemotaxis Assay

Products Cited

Cross-Reactivity

Applications

200-08M, 300-04, 300-06, 300-08, 300-09, 300-15, 300-17, 300-22, 300-28B, 300-37, 300-11, 300-12, 300-16,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

250-06, 300-11, 300-12, 300-14, 300-16, 300-20, 300-21, 300-26, 300-29A, 300-29B, 300-30, 300-31, 300-33, 300-34, 300-36, 300-38, 300-39, 300-40, 300-41, 300-43, 300-44, 300-46, 300-48, 300-55, 300-57, 200-08M, 250-04, 250-12, 250-37, 300-04, 300-06, 300-08, 300-09, 300-15, 300-17, 300-22, 300-24, 300-28A, 300-29, 300-35, 300-37, 300-45, 300-47, 300-50, 300-54, 300-56,

Bacteria

in vitro

Products Cited

Cross-Reactivity

Applications

300-22, 300-45, 300-11, 300-14, 300-39, 300-40, 300-41, 300-46,

Hamster

in vitro

Products Cited

Cross-Reactivity

Applications

300-22, 300-45, 300-11, 300-14, 300-39, 300-40, 300-41, 300-46,

Hamster

in vitro

Products Cited

Cross-Reactivity

Applications

200-02,

Human

in vitro

Human

Chemotaxis Assay

Products Cited

Cross-Reactivity

Applications

200-08, 300-30, 300-48, 300-22,

Human

in vitro

500-P28BT, 500-P28BT,

N/A

Binding Assay

Products Cited

Cross-Reactivity

Applications

300-11, 300-14, 300-29A, 300-39, 300-40, 200-08M, 300-06, 300-08, 300-09, 300-22, 300-28A,

Human

in vitro

Chemokines