Recombinant Human Exodus-2 (CCL21) 0 ReviewsSubmit a Review Product Details Catalog Number: 300-35A Description: Exodus‐2 is a CC chemokine that signals through the CCR7 receptor. It is expressed in lymphatic endothelial cells, the spleen and appendix. Exodus‐2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus‐2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant Human Exodus‐2 (CCL21) is a 12.2 kDa protein containing 111 amino acid residues.*Human Exodus-2 (Catalog Number 300-35A) has replaced Human Exodus-2 (Catalog Number 300-35) Source: E.coli Synonyms: 6Ckine, SLC AA Sequence: SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2. Calculated Molecular Weight: 12.2 kDa Accession Number: O00585 Gene ID: 6366 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Chemotaxis Immune System Inflammation Wound Healing Recent Citations First Author Du, Y Title Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation. Citation The Journal of Experimental Medicine; 219(7) PubMed ID 35640018 First Author Gurusamy, M Title G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators. Citation Nature Communications; 12(1) pg6798 PubMed ID 34815397
