Growth Factors & Cytokines

Recombinant Human FGF-4

Product Details

Catalogue Number: 100-31
Description:

FGF-4 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through FGFR 1c, 2c, 3c, and 4. Recombinant Human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-4, HST-1, Transforming protein KS3, HBGF-4

AA Sequence: GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.

Calculated Molecular Weight: 19.7 kDa

Accession Number: P08620

Gene ID: 2249

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Varberg, K M
Title
ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development.
Citation
Proceedings of the National Academy of Sciences of the United States of America; 118(10)
PubMed Id
First Author
Qi, L
Title
FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma.
Citation
Oncotarget; 7(45) pg74015-74030
PubMed Id
First Author
Dvořák, Z
Title
Targeting the pregnane X receptor using microbial metabolite mimicry.
Citation
EMBO Molecular Medicine; 12(4) pge11621
PubMed Id

product.subtitle.productreviews

Existing reviews
Great Product
We have been using this FGF-4 product to culture Trophoblast stem cells successfully. Always arrives quickly and works well.
From:  Alison | Date:  8/7/2020