Chemokines

Recombinant Human GCP-2 (CXCL6)

Product Details

Catalogue Number: 300-41
Description:

CXCL6, also known as GCP-2 in humans, is a connective tissue-derived CXC chemokine that can signal through the CXCR1 and CXCR2 receptors.  Human GCP-2, which is cross-reactive with murine cells, selectively attracts neutrophils, and has also been shown to exert anti-angiogenic activity. Recombinant Human GCP-2 is a 7.9 kDa protein containing 72 amino acid residues.

Source: E.coli

Synonyms: Granulocyte Chemotactic Protein-2, CXCL6, LIX (murine)

AA Sequence: VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.

Calculated Molecular Weight: 7.9 kDa

Accession Number: P80162

Gene ID: 6372

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Hanson, M G
Title
Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro.
Citation
The Journal of neuroscience : the official journal of the Society for Neuroscience; 18(18) pg7361-71
PubMed Id
First Author
Lee, A W
Title
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
Citation
The Journal of Biological Chemistry; 294(29) pg11199-11212
PubMed Id
First Author
Alenazi, Y
Title
Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.
Citation
Scientific Reports; 8(1) pg6333
PubMed Id