Animal-Free Recombinant Human IL-17D 0 ReviewsSubmit a Review Product Details Catalog Number: AF-200-27 Description: IL-17D is a disulfide-linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL-17 family of structurally related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8 and GM-CSF, and inhibits hemopoiesis of myeloid progenitor cells in colony-forming assays. Recombinant Human IL-17D is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Interleukin-17D AA Sequence (monomer): APRAGRRPAR PRGCADRPEE LLEQLYGRLA AGVLSAFHHT LQLGPREQAR NASCPAGGRP ADRRFRPPTN LRSVSPWAYR ISYDPARYPR YLPEAYCLCR GCLTGLFGEE DVRFRSAPVY MPTVVLRRTP ACAGGRSVYT EAYVTIPVGC TCVPEPEKDA DSINSSIDKQ GAKLLLGPND APAGP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Measured by its binding ability in a functional ELISA. Calculated Molecular Weight: 40.5 kDa Accession Number: Q8TAD2 Gene ID: 53342 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) Cross Reactivity Cited in References: Mouse PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Bone, Skeletal, Cartilage Immune System
