Recombinant Human IL-2

Product Details

Catalog Number: 200-02

Description:

IL-2 is a powerful immunoregulatory lymphokine produced by T cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Source: E.coli

Synonyms: Interleukin-2, T-cell growth factor (TCGF), Aldesleukin

AA Sequence: MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.

Calculated Molecular Weight: 15.5 kDa

Accession Number: P60568

Gene ID: 3558

Cross Reactivity Cited in References:

Bacteria, Chicken, Cow, Cow + Mouse, Dog, Human, Human + Hamster, Human + Mouse, Human + Virus, Monkey, Mouse, Rat

Research Interest